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Friday, March 1, 2019

Business Research Essay

In nows society we pass on found that the best way to point out what works for individuals and commercial enterprisees alike is done through business research. This is non constantly done in ethical manners though. Some companies tend to bear questions that are inappropriate while others changed the information they have been given to cryst every(prenominal)ise their product look more(prenominal) appealing. This paper entrust focus on skewing the research results in the service of selling the drug Neurontin.Neurontin is a send name for the drug gabapentin and it is manufactured by Pfizer and Parke-Davis (Ramirez de Arellano, 2009). The drug has been authorize by the FDA to use in treating neurological conditions such as epilepsy. There have been a large progeny of off-label uses added to the list that have not been approved by the FDA which has increased the familys sales.In 2004, Pfizer was found bloodguilty in urging physicians to prescribe Neurontin to patients for off-label uses such as give-and-take of migraines, bipolar disorder, insomnia, and hot-flashes (Ramirez de Arellano, 2009). This act was an illegal one that cost the company millions of dollars in charmings and penalties. That was not the last of the theatrical role on Neurontin.Since so many people had use Neurontin for various treatments not approved by the FDA, a large number of companies decided to show an interest in getting some of the off-label uses approved. In order to do this the companies began posting research to see if the drug re in ally worked for the ailments. If it did thusly work, it could be approved through the FDA. This would in turn help the company make more money selling Neurontin.After the legal case was started in 2004 it opened another door that provided information showing strategies that Pfizer and Parke-Davis utilise to offset the publication of unfavorable findings. In 2008 reports were released to the public that showed Pfizer and Parke-Davis h ad delayed reports if no evidence was found in the efficacy of the drug, reinterpreting negative information, and fusing negative info with positive studies to cancel the results, and some researchers saw their work being rewritten by the companys own medical write to make it run low better than the graph showed it (Ramirez de Arellano, 2009).During the studies done on Neurontin 20 clinical trials were set and only 12 of those describe in publications, in which 8 of those promulgated trials had different uncomplicated outcomes reported than was in the original research communications protocol (Ramirez de Arellano, 2009). These differences included changing the primary outcome, not distinguishing between the primary and the thirdhand outcomes, and not reporting all of the primary outcomes. There was 21 primary outcomes for the research and out of those 21 protocols there was 6 not reported and 4 were put as secondary outcomes instead of primary. The changes made in the publish ed reports were done to make Neurontin look favorable for the unapproved indications.In the Neurontin state of affairs of skewing the research done for the medication, affects the people that use the drug along with others that take any medication. It makes the doctors look as if they do not know what they are doing when they prescribe the medication and leaves individuals in an un trusting state to try some thing untested to treat their ailments. It also makes the scientists that develop the drug look bad. Another thing this does is undermines individuals trust in published studies and the entire decision-making process.The organization is affected by this unethical behavior in many ways as well. jump off the company was faced with a hefty criminal fine for coaxing the doctors to prescribe the drug to the public for off-label purposes. Secondly the company wooly-minded accreditation with the public for skewing the research being done to make the drug more appealing in what it could treat. Skewing the research affected society by losing the trust of individuals when it was made public that the research published had been tainted. It is hard to trust again when you find out the information you are being give is all but the truth.Unethical business research could be avoided if companies that do business research would publish all of the truth without changing any of it or doctoring it up to look better than it really is. If the punishment for using unethical business research were harsher it may deter companies from using unethical practices to conduct their business research. Companies that continue to be found guilty of using unethical business research should be humiliated to the point nobody would take to do business with them, forcing them to close their doors.In conclusion it can be noted that the most important part of finding the right treatments today in medicine is through clinical research data and that data has to be 100% undistorted to know whether or not the treatment is one that will do good or one that will do harm. This goes for any type of business research and should be followed with all companies.

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